Sequence of ADHE_STRPN
EC Number:1.1.1.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
alcohol dehydrogenase
A0A0H2URT2
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
883
97286
Reaction
(R)-mevalonate + NAD+ = mevaldate + NADH + H+
General information:
Sequence
0 MADKKTVTPE EKKLVAEKHV DELVQKALVA LEEMRKLDQE QVDYIVAKAS VAALDAHGEL
60 ALHAFEETGR GVFEDKATKN LFACEHVVNN MRHTKTVGVI EEDDVTGLTL IAEPVGVVCG
120 ITPTTNPTST AIFKSLISLK TRNPIVFAFH PSAQESSAHA ARIVRDAAIA AGAPENCVQW
180 ITQPSMEATS ALMNHEGVAT ILATGGNAMV KAAYSCGKPA LGVGAGNVPA YVEKSANIRQ
240 AAHDIVMSKS FDNGMVCASE QAVIIDKEIY DEFVAEFKSY HTYFVNKKEK ALLEEFCFGV
300 KANSKNCAGA KLNADIVGKP ATWIAEQAGF TVPEGTNILA AECKEVGENE PLTREKLSPV
360 IAVLKSESRE DGITKARQMV EFNGLGHSAA IHTADEELTK EFGKAVKAIR VICNSPSTFG
420 GIGDVYNAFL PSLTLGCGSY GRNSVGDNVS AINLLNIKKV GRRRNNMQWM KLPSKTYFER
480 DSIQYLQKCR DVERVMIVTD HAMVELGFLD RIIEQLDLRR NKVVYQIFAD VEPDPDITTV
540 NRGTEIMRAF KPDTIIALGG GSPMDAAKVM WLFYEQPEVD FRDLVQKFMD IRKRAFKFPL
600 LGKKTKFIAI PTTSGTGSEV TPFAVISDKA NNRKYPIADY SLTPTVAIVD PALVLTVPGF
660 VAADTGMDVL THATEAYVSQ MASDYTDGLA LQAIKLVFEN LESSVKNADF HSREKMHNAS
720 TIAGMAFANA FLGISHSMAH KIGAQFHTIH GRTNAILLPY VIRYNGTRPA KTATWPKYNY
780 YRADEKYQDI ARMLGLPAST PEEGVESYAK AVYELGERIG IQMNFRDQGI DEKEWKEHSR
840 KLAFLAYEDQ CSPANPRLPM VDHMQEIIED AYYGYKERPG RRK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
4049
Tettelin H.,Nelson K.E.,Paulsen I.T.,Eisen J.A.,Read T.D.,Peterson S.N.,Heidelberg J.F.,DeBoy R.T.,Haft D.H.,Dodson R.J.,Durkin A.S.,Gwinn M.L.,Kolonay J.F.,Nelson W.C.,Peterson J.D.,Umayam L.A.,White O.,Salzberg S.L.,Lewis M.R.,Radune D.,Holtzapple E.K.,Khouri H.M.,Wolf A.M.,Utterback T.R.,Hansen C.L.,McDonald L.A.,Feldblyum T.V.,Angiuoli S.V.,Dickinson T.,Hickey E.K.,Holt I.E.,Loftus B.J.,Yang F.,Smith H.O.,Venter J.C.,Dougherty B.A.,Morrison D.A.,Hollingshead S.K.,Fraser C.M.
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.
Science
293
498-506
2001
4050
Im H.,Pearson M.L.,Martinez E.,Cichos K.H.,Song X.,Kruckow K.L.,Andrews R.M.,Ghanem E.S.,Orihuela C.J.
Targeting NAD+ regeneration enhances antibiotic susceptibility of Streptococcus pneumoniae during invasive disease.
PLoS Biol.
21
e3002020-e3002020
2023
