Sequence of LYS2_YEAST
EC Number:1.2.1.31
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
L-aminoadipate-semialdehyde dehydrogenase
P07702
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1392
155346
Reaction
(S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O = L-2-aminoadipate + NAD(P)H + H+
General information:
Sequence
show sequence in normal format
>P07702|L-aminoadipate-semialdehyde dehydrogenase|EC 1.2.1.31|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)|Swiss-Prot
MTNEKVWIEKLDNPTLSVLPHDFLRPQQEPYTKQATYSLQLPQLDVPHDSFSNKYAVALS
VWAALIYRVTGDDDIVLYIANNKILRFNIQPTWSFNELYSTINNELNKLNSIEANFSFDE
LAEKIQSCQDLERTPQLFRLAFLENQDFKLDEFKHHLVDFALNLDTSNNAHVLNLIYNSL
LYSNERVTIVADQFTQYLTAALSDPSNCITKISLITASSKDSLPDPTKNLGWCDFVGCIH
DIFQDNAEAFPERTCVVETPTLNSDKSRSFTYRDINRTSNIVAHYLIKTGIKRGDVVMIY
SSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPRGLIVIRAAGQLDQLVED
YINDELEIVSRINSIAIQENGTIEGGKLDNGEDVLAPYDHYKDTRTGVVVGPDSNPTLSF
TSGSEGIPKGVLGRHFSLAYYFNWMSKRFNLTENDKFTMLSGIAHDPIQRDMFTPLFLGA
QLYVPTQDDIGTPGRLAEWMSKYGCTVTHLTPAMGQLLTAQATTPFPKLHHAFFVGDILT
KRDCLRLQTLAENCRIVNMYGTTETQRAVSYFEVKSKNDDPNFLKKLKDVMPAGKGMLNV
QLLVVNRNDRTQICGIGEIGEIYVRAGGLAEGYRGLPELNKEKFVNNWFVEKDHWNYLDK
DNGEPWRQFWLGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTHISQ
HPLVRENITLVRKNADNEPTLITFMVPRFDKPDDLSKFQSDVPKEVETDPIVKGLIGYHL
LSKDIRTFLKKRLASYAMPSLIVVMDKLPLNPNGKVDKPKLQFPTPKQLNLVAENTVSET
DDSQFTNVEREVRDLWLSILPTKPASVSPDDSFFDLGGHSILATKMIFTLKKKLQVDLPL
GTIFKYPTIKAFAAEIDRIKSSGGSSQGEVVENVTANYAEDAKKLVETLPSSYPSREYFV
EPNSAEGKTTINVFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQK
AGITYGTWNEKFASNIKVVLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAK
LRDPNVISTINVMSLAAVGKPKFFDFVSSTSTLDTEYYFNLSDKLVSEGKPGILESDDLM
NSASGLTGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASANGSSNTDDFLLRFLKG
SVQLGKIPDIENSVNMVPVDHVARVVVATSLNPPKENELAVAQVTGHPRILFKDYLYTLH
DYGYDVEIESYSKWKKSLEASVIDRNEENALYPLLHMVLDNLPESTKAPELDDRNAVASL
KKDTAWTGVDWSNGIGVTPEEVGIYIAFLNKVGFLPPPTHNDKLPLPSIELTQAQISLVA
SGAGARGSSAAA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
356305
Morris M.E.,Jinks-Robertson S.
Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.
Gene
98
141-145
1991
356306
Mannhaupt G.,Stucka R.,Ehnle S.,Vetter I.,Feldmann H.
Analysis of a 70 kb region on the right arm of yeast chromosome II.
Yeast
10
1363-1381
1994
356307
Feldmann H.,Aigle M.,Aljinovic G.,Andre B.,Baclet M.C.,Barthe C.,Baur A.,Becam A.-M.,Biteau N.,Boles E.,Brandt T.,Brendel M.,Brueckner M.,Bussereau F.,Christiansen C.,Contreras R.,Crouzet M.,Cziepluch C.,Demolis N.,Delaveau T.,Doignon F.,Domdey H.,Duesterhus S.,Dubois E.,Dujon B.,El Bakkoury M.,Entian K.-D.,Feuermann M.,Fiers W.,Fobo G.M.,Fritz C.,Gassenhuber J.,Glansdorff N.,Goffeau A.,Grivell L.A.,de Haan M.,Hein C.,Herbert C.J.,Hollenberg C.P.,Holmstroem K.,Jacq C.,Jacquet M.,Jauniaux J.-C.,Jonniaux J.-L.,Kallesoee T.,Kiesau P.,Kirchrath L.,Koetter P.,Korol S.,Liebl S.,Logghe M.,Lohan A.J.E.,Louis E.J.,Li Z.Y.,Maat M.J.,Mallet L.,Mannhaupt G.,Messenguy F.,Miosga T.,Molemans F.,Mueller S.,Nasr F.,Obermaier B.,Perea J.,Pierard A.,Piravandi E.,Pohl F.M.,Pohl T.M.,Potier S.,Proft M.,Purnelle B.,Ramezani Rad M.,Rieger M.,Rose M.,Schaaff-Gerstenschlaeger I.,Scherens B.,Schwarzlose C.,Skala J.,Slonimski P.P.,Smits P.H.M.,Souciet J.-L.,Steensma H.Y.,Stucka R.,Urrestarazu L.A.,van der Aart Q.J.M.,Van Dyck L.,Vassarotti A.,Vetter I.,Vierendeels F.,Vissers S.,Wagner G.,de Wergifosse P.,Wolfe K.H.,Zagulski M.,Zimmermann F.K.,Mewes H.-W.,Kleine K.
Complete DNA sequence of yeast chromosome II.
EMBO J.
13
5795-5809
1994
356308
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
356309
Fleig U.N.,Pridmore R.D.,Philippsen P.
Construction of LYS2 cartridges for use in genetic manipulations of Saccharomyces cerevisiae.
Gene
46
237-245
1986
356310
Mannhaupt G.,Stucka R.,Ehnle S.,Vetter I.,Feldmann H.
Molecular analysis of yeast chromosome II between CMD1 and LYS2: the excision repair gene RAD16 located in this region belongs to a novel group of double-finger proteins.
Yeast
8
397-408
1992
356311
Schaaff-Gerstenschlaeger I.,Mannhaupt G.,Vetter I.,Zimmermann F.K.,Feldmann H.
TKL2, a second transketolase gene of Saccharomyces cerevisiae. Cloning, sequence and deletion analysis of the gene.
Eur. J. Biochem.
217
487-492
1993
356312
Ehmann D.E.,Gehring A.M.,Walsh C.T.
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.
Biochemistry
38
6171-6177
1999
356313
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
356314
Starita L.M.,Lo R.S.,Eng J.K.,von Haller P.D.,Fields S.
Sites of ubiquitin attachment in Saccharomyces cerevisiae.
Proteomics
12
236-240
2012
