EC Number   |
Protein Variants |
Reference |
|---|
   6.3.4.18 | D153A |
mutation without affecting substrate binding but critical role in catalysis, decrease in catalytic proficiency |
702382 |
| 6.3.4.18 | D153A |
the mutant shows wild type activity |
727030 |
| 6.3.4.18 | E73A |
mutation with affect on substrate binding, decrease in catalytic proficiency |
702382 |
| 6.3.4.18 | E73A |
the mutant shows 2fold reduced activity compared to the wild type enzyme |
-, 727030 |
| 6.3.4.18 | F78I |
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme |
-, 726578 |
| 6.3.4.18 | F78W |
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme |
-, 726578 |
| 6.3.4.18 | H273A |
inactive |
-, 727030 |
| 6.3.4.18 | H273Q |
inactive |
727030 |
| 6.3.4.18 | K353A |
inactive |
-, 727030 |
| 6.3.4.18 | K353A |
mutation without affecting substrate binding but critical role in catalysis, decrease in catalytic proficiency |
702382 |
