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EC Number
Protein Variants
Commentary
Reference
5.4.2.12
D12N
no activity
650970
5.4.2.12
D319A
site-directed mutagenesis, substitution of the metal-binding residue Asp319 by Ala results in complete loss of independent PGAM activity
727472
5.4.2.12
H123N
3% of wild-type activity
650970
5.4.2.12
H125N
67% of wild-type activity
650970
5.4.2.12
H128N
20% of wild-type activity
650970
5.4.2.12
H23A
no enzymic activity. Like wild-type, mutant forms a dimer
679715
5.4.2.12
H407N
no activity
650970
5.4.2.12
H42N
91% of wild-type activity
650970
5.4.2.12
H42N/H128N
8% of wild-type activity
650970
5.4.2.12
H445N
18% of wild-type activity
650970
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