EC Number   |
Protein Variants |
Reference |
|---|
    5.1.1.13 | C194A |
site-directed mutagenesis, inactive mutant |
-, 747721 |
| 5.1.1.13 | C82A |
catalytically inactive. Crystallization data in complex with citric acid |
-, 695052 |
| 5.1.1.13 | C82A |
inactive |
-, 716952 |
| 5.1.1.13 | C83A |
site-directed mutagenesis, inactive mutant |
-, 747721 |
| 5.1.1.13 | C83A/C194A |
site-directed mutagenesis, inactive mutant |
-, 747721 |
| 5.1.1.13 | K136W |
the importance of lysine-136, the presumed proton donor, is highlighted by its mutation to tryptophan, which virtually abolishes racemase activity |
706558 |
| 5.1.1.13 | more |
generation of Got1l1 knockout mice. Got1l1 mRNA is highly expressed in the testis in wild-type mice, but is not detected in Got1l1 knockout mice. The D-aspartate contents of knockout and Got1l1 knockout mice are not significantly different in the testis and hippocampus |
746719 |
| 5.1.1.13 | more |
knockdown of Got1l1 in cultured GH3 cells |
746721 |
| 5.1.1.13 | more |
knockdown of Got1l1 in HeLa cells |
746721 |
| 5.1.1.13 | more |
substituting the triple serine loop region in AspRs enhances serine racemization |
746724 |
