EC Number |
Protein Variants |
Reference |
---|
4.2.3.3 | D100N |
the mutant shows reduced catalytic efficiency compared to the wild type enzyme |
747957 |
4.2.3.3 | D100V |
the mutant shows reduced catalytic efficiency compared to the wild type enzyme |
747957 |
4.2.3.3 | D101E |
reduced ratio of turnover-numer:Km-value by about 10000fold compared to the wild-type enzyme |
137616 |
4.2.3.3 | D101N |
reduced ratio of turnover-numer:Km-value by about 10000fold compared to the wild-type enzyme |
137616 |
4.2.3.3 | D10N |
almost complete loss of activity |
729488 |
4.2.3.3 | D71E |
reduced ratio of turnover-numer:Km-value by about 1000fold compared to the wild-type enzyme |
137616 |
4.2.3.3 | D71N |
2500fold decrease in kcat |
650074 |
4.2.3.3 | D71N |
reduced ratio of turnover-numer:Km-value by about 1000fold compared to the wild-type enzyme |
137616 |
4.2.3.3 | DELTAR97 |
strong decrease in activity, increase in Hill coefficient from 1 of wild-type to 3.3 |
729948 |
4.2.3.3 | G56A |
significant increase in Hill coefficient, large decrease in turnover number |
730866 |