EC Number |
Protein Variants |
Reference |
---|
4.2.3.23 | A435T |
site-directed mutagenesis, altered kinetics but similar activity compared to the wild-type enzyme |
661381 |
4.2.3.23 | E428D |
the mutation leads to gain of an ubiquitination site in position 432 |
748660 |
4.2.3.23 | K227E |
the mutation leads to gain of a serine phosphorylation site in position 224 |
748660 |
4.2.3.23 | more |
deletion of the N-terminal 44 amino acid residues leads to loss of 90% of catalytic activity |
662712 |
4.2.3.23 | R68G |
the mutation leads to loss of a predicted serine phosphorylation site in position 71 |
748660 |
4.2.3.23 | S434A |
site-directed mutagenesis, activity and kinetics similar to the wild-type enzyme |
661381 |
4.2.3.23 | S434T/A435T |
site-directed mutagenesis, inactive mutant |
661381 |
4.2.3.23 | T270N |
the mutation does not interfere with protein function |
748660 |
4.2.3.23 | T433A |
site-directed mutagenesis, altered kinetics and reduced activity compared to the wild-type enzyme |
661381 |
4.2.3.23 | T433A/A435T |
site-directed mutagenesis, altered kinetics and reduced activity compared to the wild-type enzyme |
661381 |