EC Number |
Protein Variants |
Reference |
---|
4.2.3.13 | D307A |
aspartate-rich motif interacts with putative Mg2+ |
702321 |
4.2.3.13 | D308A |
aspartate-rich motif interacts with putative Mg2+ |
702321 |
4.2.3.13 | D311A |
aspartate-rich motif interacts with putative Mg2+ |
702321 |
4.2.3.13 | D451A |
aspartate-rich motif interacts with putative Mg2+ |
702321 |
4.2.3.13 | D452A |
aspartate-rich motif interacts with putative Mg2+ |
702321 |
4.2.3.13 | E455A |
aspartate-rich motif interacts with putative Mg2+ |
702321 |
4.2.3.13 | L405H |
mutation alters product selectivity from (+)-d-cadinene to germacrene D-4-ol (53%). Mutation improves the solubility of the enzyme |
679169 |
4.2.3.13 | more |
if W279 in delta-cadinene synthase is replaced with various smaller amino acids, the ratio of alcohol versus hydrocarbon product is directly proportional to the van der Waals volume of the amino acid side chain |
747551 |
4.2.3.13 | N403P |
mutation significantly alters the product selectivity to germacrene D-4-ol (52%) |
679169 |
4.2.3.13 | N403P/L405H |
mutant maintains its specific activity and shows higher selectivity to germacrene D-4-ol in vivo (up to 93%) |
679169 |