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EC Number	Protein Variants	Commentary	Reference
4.2.3.126	H255P	site-directed mutagenesis, modification of the H-alpha1 loop, the mutant shows highly altered product profile compared to the wild-type enzyme, it does no longer produce gamma-muurolene but large amounts of germacrene A (77%), overview	713839
4.2.3.126	K251I	site-directed mutagenesis, modification of the H-alpha1 loop, the mutant shows only slightly altered product profile compared to the wild-type enzyme, it produces also beta-copaene, cf. EC 4.2.3.127, overview	713839

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Release 2023.1 (January 2023)