EC Number |
Protein Variants |
Reference |
---|
4.1.1.64 | more |
gene knockout mutants display wild-type morphology and pathogenicity, can use alanine as sole nitrogen source, but not 2-methylalanine |
650912 |
4.1.1.64 | Q52A |
85fold decrease in turnover number for decarboxylation half-reaction with 2-aminoisobutyrate and pyruvate, greatly reduced rate of transamination half-reaction and impaired pyridoxamine phosphate binding |
661182 |
4.1.1.64 | Q52E |
10000fold decrease in turnover number for decarboxylation half-reaction with 2-aminoisobutyrate and pyruvate, transamination rate is nearly identical to wild-type value |
661182 |
4.1.1.64 | Q52I |
100000fold decrease in turnover number for decarboxylation half-reaction with 2-aminoisobutyrate and pyruvate, greatly reduced rate of transamination half-reaction and impaired pyridoxamine phosphate binding |
661182 |