EC Number |
Protein Variants |
Reference |
---|
4.1.1.25 | A295F |
site-directed saturation mutagenesis, the mutant shows reduced activity compared to wild-type |
749322 |
4.1.1.25 | E102A |
site-directed saturation mutagenesis, the mutant shows reduced activity compared to wild-type |
749322 |
4.1.1.25 | E299A |
site-directed saturation mutagenesis, the mutant shows reduced activity compared to wild-type |
749322 |
4.1.1.25 | F338Y |
alteration in the primary activity from decarboxylation/deamination to decarboxylation. Mutant displays a very low activity to tyrosine, i.e. about 5% of its activity to phenylalanine, and strong activity to DOPA |
727952 |
4.1.1.25 | F346Y |
alteration in the primary activity from decarboxylation-deamination to decarboxylation. Mutant retains a small percentage of decarboxylation-deamination activity |
727952 |
4.1.1.25 | G296F |
site-directed saturation mutagenesis, the mutant shows reduced activity compared to wild-type |
749322 |
4.1.1.25 | H241N |
site-directed saturation mutagenesis, almost inactive mutant |
749322 |
4.1.1.25 | H241Q |
site-directed saturation mutagenesis, almost inactive mutant |
749322 |
4.1.1.25 | H391A |
site-directed saturation mutagenesis, the mutant shows reduced activity compared to wild-type |
749322 |
4.1.1.25 | H98A |
site-directed saturation mutagenesis, the mutant shows reduced activity compared to wild-type |
749322 |