EC Number |
Protein Variants |
Reference |
---|
3.7.1.5 | D102A |
site-directed mutagenesis |
719974 |
3.7.1.5 | E33A |
significant reduction in oxaloacetate decarboxylase activity and complete abrogation of the acylpyruvate hydrolase activity |
756006 |
3.7.1.5 | H30A |
significant reduction in oxaloacetate decarboxylase activity and complete abrogation of the acylpyruvate hydrolase activity |
756006 |
3.7.1.5 | K123A |
oxaloacetate decarboxylase activity and acylpyruvate hydrolase activity are abolished |
756006 |
3.7.1.5 | more |
lentiviral shRNA knockdown of FAHD1 in human umbilical vein cells |
719974 |
3.7.1.5 | more |
mutation of amino acids H30, E33 and K123 each had discernible influence on the acylpyruvate hydrolase and/or oxaloacetate decarboxylase activity of FAHD1, suggesting distinct catalytic mechanisms for both activities |
756006 |
3.7.1.5 | R106A |
site-directed mutagenesis |
719974 |