EC Number |
Protein Variants |
Reference |
---|
3.5.3.12 | C157G |
the mutant of inactive isoform AguA2 shows wild type enzyme activity |
734228 |
3.5.3.12 | C180A |
site-directed mutagenesis, conserved catalytically relevant Cys, 35% of wild-type activity, inhibition with iodoacetamide is easier abolished by substrate agmatine |
655571 |
3.5.3.12 | C315S |
enzymatically inactive form |
-, 752778 |
3.5.3.12 | C356A |
inactive |
734228 |
3.5.3.12 | C361A |
20% enzyme activity of wild-type enzyme |
685687 |
3.5.3.12 | C364G |
complete loss of activity |
713057 |
3.5.3.12 | C366A |
site-directed mutagenesis, conserved catalytically relevant Cys, 15% of wild-type activity, inhibition with iodoacetamide is easier abolished by substrate agmatine |
655571 |
3.5.3.12 | D218A |
inactive |
-, 734228 |
3.5.3.12 | D218E |
inactive |
-, 734228 |
3.5.3.12 | D94A |
inactive |
-, 734228 |