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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.43C241A C2 mutation, behaves similarly to the wild-type enzyme with slightly elevated hemolytic activity 695326
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.43Q243G C2 mutation reduces C4b2a sensitivity to decay-accelerating factor DAF to 2% of the wild-type, moderately reduces C4b2a sensitivity to complement receptor 1-A to 55% of the wild-type 652494
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.43Y327A C2 mutation reduces C4b2a sensitivity to decay-accelerating factor DAF and to complement receptor 1-A to less than 1% of the wild-type 652494
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