EC Number |
Protein Variants |
Reference |
---|
3.4.14.4 | C113S |
mutation of the cysteine residue |
707596 |
3.4.14.4 | C130S |
mutant, only existence of dimeric form |
707596 |
3.4.14.4 | C130S |
the mutant exhibits comparable enzymatic activity to the wild type protein |
-, 698782 |
3.4.14.4 | C147A |
activity similar to wild type |
649555 |
3.4.14.4 | C176A |
25-35% of wild type activity, resistant against p-chloro-mercuri-benzoate and N-ethylmaleimide |
649555 |
3.4.14.4 | C176E |
no enzymic activity |
649555 |
3.4.14.4 | C176G |
no enzymic activity |
649555 |
3.4.14.4 | C19A |
activity similar to wild type |
649555 |
3.4.14.4 | C450S |
residues Gly383 and Glu320 form significantly less hydrogen bonds with substrate Arg-Arg-2-naphthylamide than in the wild type enzyme |
754693 |
3.4.14.4 | C509A |
activity similar to wild type |
649555 |