EC Number   |
Protein Variants |
Reference |
|---|
  3.1.3.78 | C438S |
site-directed mutagenesis |
697606 |
| 3.1.3.78 | C462A |
recombinant protein |
697201 |
| 3.1.3.78 | C462S |
does not restore the ability of Salmonella to eliminate phosphatidylinositol 4,5-bisphosphate in SigD-deficient bacteria |
700351 |
| 3.1.3.78 | C462S |
no functional or morphological changes in epithelial cells transfected with phosphatase-deficient mutant C462S |
681168 |
| 3.1.3.78 | DELTA1-135-DELTA118-142 |
recombinant protein, Saccharomyces cerevisiae: no effect in Saccharomyces cerevisiae, HeLa: no effect (Green Fluorescent Protein linked) in HeLa |
697201 |
| 3.1.3.78 | DELTA1-165 |
recombinant protein, Saccharomyces cerevisiae: strong impact on actin filaments and budding, HeLa (Green Fluorescent Protein linked): loss of adherence and strong impact on actin filaments |
697201 |
| 3.1.3.78 | DELTA1-351 |
recombinant protein, Saccharomyces cerevisiae: strong impact on actin filaments and budding, HeLa (Green Fluorescent Protein linked): loss of adherence and strong impact on actin filaments |
697201 |
| 3.1.3.78 | DELTA118-142 |
recombinant protein, Saccharomyces cerevisiae: strong impact on actin filaments and budding, residues 118142 crucial for toxicity of SigD in the yeast cells, affecting both phosphatase activity and actin depolarization events, no effect (Green Fluorescent Protein linked) in HeLa |
697201 |
| 3.1.3.78 | DELTA352-563 |
recombinant protein, no effect in Saccharomyces cerevisiae, no effect in HeLa (Green Fluorescent Protein linked) |
697201 |
| 3.1.3.78 | K527A |
restores the ability of Salmonella to eliminate phosphatidylinositol 4,5-bisphosphate in SigD-deficient bacteria |
700351 |
