EC Number |
Protein Variants |
Reference |
---|
3.1.3.76 | C154Y |
site-directed mutagenesis, the mutant shows a hydrolase/phosphatase ratio of 2.2, compared to the wild-type ratio of 1.0 |
660799 |
3.1.3.76 | C154Y |
the mutant shows similar activity for isoprenoid phosphate compared to the wild-type enzyme |
660928 |
3.1.3.76 | D9A |
site-directed mutagenesis, inactive mutant N-terminal domain |
663199 |
3.1.3.76 | E470G |
site-directed mutagenesis, the mutant shows a hydrolase/phosphatase ratio of 0.9, compared to the wild-type ratio of 1.0 |
660799 |
3.1.3.76 | K55R |
site-directed mutagenesis, the mutant shows a hydrolase/phosphatase ratio of 1.9, compared to the wild-type ratio of 1.0 |
660799 |
3.1.3.76 | more |
the isolated recombinant N-terminal domain is a fully active phosphatase |
663199 |
3.1.3.76 | R103C |
site-directed mutagenesis, the mutant shows a hydrolase/phosphatase ratio of 1.3, compared to the wild-type ratio of 1.0 |
660799 |
3.1.3.76 | R103C |
the mutant shows increased activity for isoprenoid phosphate compared to the wild-type enzyme |
660928 |
3.1.3.76 | R103C/R287Q |
site-directed mutagenesis, the mutant shows a hydrolase/phosphatase ratio of 1.2, compared to the wild-type ratio of 1.0 |
660799 |
3.1.3.76 | R103C/R287Q |
the mutant shows similar activity for isoprenoid phosphate compared to the wild-type enzyme |
660928 |