EC Number   |
Protein Variants |
Reference |
|---|
   3.1.21.5 | D138A |
catalytically inactive |
694446 |
| 3.1.21.5 | D354A |
mutant shows reduced activity compared to the wild type enzyme |
691509 |
| 3.1.21.5 | D898A |
Res subunit, no enzymic activity |
652848 |
| 3.1.21.5 | E350A |
mutant shows reduced activity compared to the wild type enzyme |
691509 |
| 3.1.21.5 | E916A |
Res subunit, no enzymic activity |
652848 |
| 3.1.21.5 | F353A |
mutant shows reduced activity compared to the wild type enzyme |
691509 |
| 3.1.21.5 | G448S |
mutant of Mod subunit, not able to bind S-adenosyl-L-methionine, no DNA cleavage |
652861 |
| 3.1.21.5 | K918A |
Res subunit, no enzymic activity |
652848 |
| 3.1.21.5 | more |
analysis of several strains for phase variable methyltransferase activity, mod, and restriction endonuclease activity. Of 41 strains in the survey that contain a phase variable mod gene, seven have an obvious mutation in the restriction domain and appear to be dedicated phasevarions. The remaining 15 strains that do not contain a phase variable mod gene are likely to be dedicated, functional, type III restriction-modification systems |
683939 |
| 3.1.21.5 | more |
mutant c2-134, unable to cleave DNA, mutant c2-440, poor ability to cleave DNA |
652861 |
