EC Number   |
Protein Variants |
Reference |
|---|
   2.8.2.30 | K259A |
the mutant shows 13.1% activity compared to the wild type enzyme |
726389 |
| 2.8.2.30 | more |
a synthetic siRNA duplex, si3-OST-3, corresponding to 3-OST-3 mRNA sequences is used to inhibit the expression of mRNAs encoding 3-OST-3 isoforms, downregulation of the expression of 3-OST-3 by RNA interference potently reduced CyPB binding and consequent activation of p44/42 mitogen-activated protein kinases, overview |
674849 |
| 2.8.2.30 | more |
construction of a truncated version of 3-OST-3A starting at amino acid position G148, thereby lacking the cytoplasmic, transmembrane and SPLAG domain |
691054 |
| 2.8.2.30 | more |
enzyme HS3ST3B1 knockout using siRNA |
761577 |
| 2.8.2.30 | more |
expression of 3-OST-3 leads to cell-to-cll fusion activity in CHO-K1 cells via gD receptors modified with 3-OS HS generated by 3-OST-3, overview |
677244 |
| 2.8.2.30 | more |
generation of a truncated mutant enzyme depleted of its catalytic domain. The mutant shows the same localization in the Golgi as the wild-type full-length enzyme |
760623 |
| 2.8.2.30 | more |
generation of stable HS3STA knockdown A-549 cell line by shRNA resulting in in vitro metastasis capability of A549 cell line |
761220 |
| 2.8.2.30 | T256A |
the mutant shows 101.5% activity compared to the wild type enzyme |
726389 |
| 2.8.2.30 | T256E |
the mutant shows 13.1% activity compared to the wild type enzyme |
726389 |
| 2.8.2.30 | T256V |
the mutant shows 59.4% activity compared to the wild type enzyme |
726389 |
