Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Protein Variants

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 11 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24D32A the mutant shows a catalytic efficiency of only 5% of the native enzyme 723528
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24D32E the mutant shows increased catalytic efficiency compared to the wild type enzyme 723528
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24D32N the mutant shows an almost 2.54times increased Km value for 3'-dephospho-CoA compared to the wild type enzyme. The absence of magnesium completely ablates activity for the D32N mutant 723528
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24G8A this mutation does not change either the Km or the Kcat of the reaction considerably 723528
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24K14A the substitution affects the kinetic parameters of the reaction resulting in a mere 19% reduction in the Kcat of the enzyme, the mutant demonstrates a 50% increase in the Km for ATP 723528
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24L114A the mutation results in a decrease in the affinity of the enzyme for the acceptor substrate 723528
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24more disruption of the TK1697 resulting in CoA auxotrophy. The DELTATK1697 mutant is inoculated in ASW-YT-pyruvate-agmatine medium, but no growth is observed. When 1 mM CoA is added to the medium, the growth defect is partially complemented, with lower growth rate and less cell yield than the wild-type strain KPD1. In the strain transformed with pRPETK1697, the growth defect is almost fully complemented -, 759707
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24more experiments to generate a single gene deletion of DPCK in Plasmodium yoelii 17X-NL parasites show that the inability to delete PyPPAT and PyDPCK is not due to a technical reason, nor the inability to access the gene loci, but due to a crucial role that both enzymes play in the growth and/or survival of blood stage parasites in mouse erythrocytes 759223
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24more generation of trophozoites of Ehdpck1 and Ehdpck2 gene-silenced strains. Ehdpck1 and Ehdpck2 gene-silenced strains show significant growth defect in normal growth medium. The level of growth inhibition by Ehdpck2 gene silencing is more severe compared to that by Ehdpck1 gene silencing 759246
Show all pathways known for 2.7.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.24R140A this mutation completely abolishes kinetic activity 723528
Results 1 - 10 of 11 > >>