EC Number |
Protein Variants |
Reference |
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2.7.1.154 | more |
different types of deficiency of PI3KC2beta are induced in mouse, i.e. global deficiency, and heterozygous kinase-dead inactivating mutation, phenotypes, overview |
761670 |
2.7.1.154 | more |
disruption of gene Pik3c2alpha. Insertion of a gene trap vector encoding a splice acceptor beta-galactosidase (trap) and a polyA stop site into the Pik3c2alpha locus occur either between exons 19 and 20 (Pik3c2alphagt1) or exons 23 and 24 (Pik3c2alphagt2), and is predicted to yield a truncated fusion protein of the first 837 or 1029 amino acids of PI3KC2alpha-linked to beta-galactosidase, respectively. shRNA expression using the cytomegalovirus (CMV) promoter |
739146 |
2.7.1.154 | more |
enzyme downregulation by specific shRNA in MCF-7, T-47D, and MDA-MB-231 cancer cells |
739216 |
2.7.1.154 | more |
generation of PI3KC2beta-silenced neuroblastoma cell lines |
737972 |
2.7.1.154 | more |
global deficiency of PI3KC2gamma is induced in mouse, phenotype, overview |
761670 |
2.7.1.154 | more |
knockdown of PI3K-C2alpha by specific siRNA in human umbilical vein endothelial cells |
738668 |
2.7.1.154 | more |
several types of deficiency of PI3KC2alpha are induced in mouse, i.e. hypomorph (global but variable), global deficiency, endothelial-cell-specific deficiency, induced endothelial-cell-specific deficiency, induced global deficiency, heterozygous kinase-dead inactivating mutation, phenotypes, overview |
761670 |
2.7.1.154 | more |
siRNA-mediated knockdown of PI3K protein expression in human umbilical vein endothelial cells |
761736 |
2.7.1.154 | more |
siRNA-mediated knockdown of PI3K protein expression in human umbilical vein endothelial cells. mCherry-C2beta overexpression stimulates pinocytosis through the mechanisms involving GFP-ITSN1-mediated recruitment of mCherry-C2beta |
761736 |
2.7.1.154 | more |
the catalytically inactive mutant of class II isozyme PI3K_68D can bind the Drk adaptor protein in vitro |
662852 |