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EC Number
Protein Variants
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2.6.1.39
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enzyme disruption mutant, needs longer lag phase for growth and shows slower growth in minimal medium. Addition of alpha-aminoadipate or lysine shortens the lag phase and improves growth rate
659885
2.6.1.39
R23A
the mutation causes 4.1fold increase in the Km value for L-2-aminoadipate, the Km value for L-Glu increases 546fold, the Km value for L-Leu is not greatly affected
702069
2.6.1.39
R23Q
the mutation causes 13.7fold increase in the Km value for L-2-aminoadipate, the Km value for L-Glu increases 134fold, the Km value for L-Leu is not greatly affected
702069
2.6.1.39
S20E
the mutant shows decreased kcat values compared to the wild type enzyme
702069
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