EC Number   |
Protein Variants |
Reference |
|---|
   2.5.1.94 | G131S |
the mutation leads to the complete loss of all SalL halogenase activities and the inability to crystallize SalL |
713086 |
| 2.5.1.94 | G131S |
the mutation results in instability and arrested chlorination |
708247 |
| 2.5.1.94 | more |
construction of an aclH deletion mutant of Aspergillus oryzae RIB40 strain, that is inactive with 3-chloro-L-tyrosine and 3-chloro-DL-phenylalanine. The DaclH mutant culture accumulates dechloroaspirochlorine. Complementation by ectopic integration of aclH in the DaclH mutant restores aspirochlorine production |
-, 737445 |
| 2.5.1.94 | more |
gene replacement of gene salL from Salinispora tropica by gene flA, EC 2.5.1.63, encoding fluorinase from Streptomaces cattleya, the recombinant fluorinase is functional in Salinispora tropica |
738049 |
| 2.5.1.94 | W129F |
the mutant shows 52% chlorinase activity, 76% brominase activity, and 3% iodidase activity compared to the wild type enzyme |
713086 |
| 2.5.1.94 | Y70T |
the mutation leads to a 1000fold loss of chlorination activity |
708247 |
| 2.5.1.94 | Y70T |
the mutation results in a two-orders-of-magnitude reduction of SalL activity, the mutant shows 0.07% chlorinase activity, 0.1% brominase activity, and 0.4% iodidase activity compared to the wild type enzyme |
713086 |
| 2.5.1.94 | Y70T/G131S |
the mutant shows 0.3% chlorinase activity, 0.5% brominase activity, and no iodidase activity compared to the wild type enzyme |
713086 |
