EC Number   |
Protein Variants |
Reference |
|---|
   2.5.1.46 | D218A |
mutation in catalytic site of subunit DHSp, mutant is unable to catalyze the single-turnover formation of NADH |
-, 760209 |
| 2.5.1.46 | D238A |
NAD-site mutant, less than 5% activity of wild-type |
638068 |
| 2.5.1.46 | D243A |
spermidine-site mutant, no spermidine-binding |
638068 |
| 2.5.1.46 | D313A |
unable to bind eIF5A-precursor, no synthesis of deoxyhypusine |
638068 |
| 2.5.1.46 | D314A |
site-directed mutagenesis, the mutant is active as deoxyhypusine synthase, but inactive as deoxyhypusine hydroxylase |
-, 737787 |
| 2.5.1.46 | D316A |
spermidine-site mutant, no spermidine-binding |
638068 |
| 2.5.1.46 | D342A |
NAD-site mutant, less than 5% activity of wild-type |
638068 |
| 2.5.1.46 | D405A |
mutation in catalytic site of subunit DHSc, impaired in activity |
-, 760209 |
| 2.5.1.46 | E103A |
mutation in catalytic site of subunit DHSp, impaired in activity |
-, 760209 |
| 2.5.1.46 | E104A |
mutation in catalytic site of subunit DHSp, impaired in activity |
760209 |
