EC Number   |
Protein Variants |
Reference |
|---|
    2.5.1.106 | E102Q |
mutation reduces the production of tryprostatin B to undetectable amounts |
-, 722449 |
| 2.5.1.106 | G115A |
no change in prenylation position of product |
-, 722449 |
| 2.5.1.106 | G115A |
significantly increased acceptance of 1-naphthol and other hydroxynaphthalenes by the mutant enzyme |
758677 |
| 2.5.1.106 | G115A/Y205C |
significantly increased acceptance of 1-naphthol and other hydroxynaphthalenes by the mutant enzyme |
758677 |
| 2.5.1.106 | G115I |
complete loss of activity |
722449 |
| 2.5.1.106 | G115L |
formation of tryprostatin B is abolished, formation of a new product occurs |
-, 722449 |
| 2.5.1.106 | G115T |
0.4% of wild-type activity in formation of trytrostatin B. Mutant catalyzes the formation of a different product that carries a reverse prenyl moiety at the C-3 of the indole nucleus |
-, 722449 |
| 2.5.1.106 | G115T |
the mutant produces a five-membered ring compound as the major product with tryprostatin B as the minor product |
758796 |
| 2.5.1.106 | H279F |
70% of wild-type activity |
-, 722449 |
| 2.5.1.106 | Y205A |
mutant produces 70.3% C3-regularly prenylated product |
-, 737520 |
