EC Number |
Protein Variants |
Reference |
---|
2.3.1.282 | A382F |
almost complete loss of activity |
-, 749897 |
2.3.1.282 | A382M |
35% of wild-type activity with substrate 1-octanol, 39% with 5R,7R-undecane-5,7-diol, 48% with pentadecane-5,7-diol, respectively |
-, 749897 |
2.3.1.282 | D128A |
mutation in HHx3DGx13Y motif, loss of activity |
-, 752024 |
2.3.1.282 | G129L |
13% of wild-type activity with substrate 1-octanol, 4% with 5R,7R-undecane-5,7-diol, 13% with pentadecane-5,7-diol, respectively |
-, 749897 |
2.3.1.282 | H123A |
about 1.7- to 2.3fold decrease in ester formation |
-, 752024 |
2.3.1.282 | H124A |
mutation in HHx3DGx13Y motif, loss of activity |
-, 752024 |
2.3.1.282 | Q19K |
16% of wild-type activity with substrate 1-octanol, 11% with pentadecane-5,7-diol, respectively |
749897 |
2.3.1.282 | Q19R |
68% of wild-type activity with substrate 1-octanol, 48% with 5R,7R-undecane-5,7-diol, 45% with pentadecane-5,7-diol, respectively |
-, 749897 |
2.3.1.282 | S380M |
almost complete loss of activity |
-, 749897 |
2.3.1.282 | V16C/G328C |
8% of wild-type activity with with 5R,7R-undecane-5,7-diol, 3% with pentadecane-5,7-diol, respectively |
749897 |