EC Number   |
Protein Variants |
Reference |
|---|
  2.3.1.253 | A181S |
the mutant shows 110% of wild type specific activity |
-, 739936 |
| 2.3.1.253 | A185D |
inactive |
740681 |
| 2.3.1.253 | A289R |
the mutant shows 1.4fold improved catalytic efficiency compared to the wild type enzyme |
-, 740985 |
| 2.3.1.253 | A60L |
the mutant still retains the wild type activity to react with lauroyl-CoA |
740681 |
| 2.3.1.253 | A82T |
the mutant shows wild type specific activity |
-, 739936 |
| 2.3.1.253 | H24L |
the mutant shows reduced reactivity toward lauroyl-CoA and has lost the ability to produce phloroglucinol |
-, 740681 |
| 2.3.1.253 | H24V |
the mutation significantly reduces the reactivity of the enzyme with lauroyl-CoA while still retaining its physiological activity to synthesize phloroglucinol |
-, 740681 |
| 2.3.1.253 | K210L |
the mutant shows 1.9fold improved catalytic efficiency compared to the wild type enzyme |
-, 740985 |
| 2.3.1.253 | K210L/Y256R |
the mutant shows 0.9fold improved catalytic efficiency compared to the wild type enzyme |
-, 740985 |
| 2.3.1.253 | L136M/S243T |
the mutant shows 90% of wild type specific activity |
-, 739936 |
