EC Number |
Protein Variants |
Reference |
---|
2.3.1.16 | C382A |
site-directed mutagenesis |
735368 |
2.3.1.16 | C92A |
site-directed mutagenesis |
735368 |
2.3.1.16 | G432R |
identification, and DNA and amino acid sequence determination, of a truncated isozyme Pex5p mutant in SK32 CHO cells, which show retarded maturation of 3-ketoacyl-CoA thiolase and acyl-CoA oxidase, and a mislocation of catalase to the cytosol, the precursor form of thiolase is only partially processed to the mature form in a temperature-sensitive manner in the Pex5pM mutant, overview |
674357 |
2.3.1.16 | H352A |
3.3fold increase in KM-value for acetoacetyl-CoA compared to wild-type value, Vmax is decreased 1154 times |
660434 |
2.3.1.16 | H352E |
2.7fold increase in KM-value for acetoacetyl-CoA compared to wild-type value, Vmax is decreased 1250 times |
660434 |
2.3.1.16 | H352K |
3.7fold increase in KM-value for acetoacetyl-CoA compared to wild-type value, Vmax is decreased 526 times |
660434 |
2.3.1.16 | H352Y |
3.1fold increase in KM-value for acetoacetyl-CoA compared to wild-type value, Vmax is decreased 429 times |
660434 |
2.3.1.16 | more |
functional expression in Sacchaormyces cerevisiae confers its elongase activity on C18DELTA6 polyunsaturated fatty acid |
705468 |
2.3.1.16 | more |
T-DNA insertion, using Agrobacterium tumefaciens-mediated random mutagenesis, between the genes encoding a class 4 alcohol dehydrogenase and the 3-ketoacyl-CoA thiolase in Leptosphaeria maculans causes increased gene expression and production of the functional enzyme leading to reduced pathogenicity of the mutant fungus on Brassica napus plant cotyledons, overview |
676105 |