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Results 1 - 5 of 5
EC Number Protein Variants Commentary Reference
Show all pathways known for 2.1.4.1Display the word mapDisplay the reaction diagram Show all sequences 2.1.4.1F245N site-directed mutagenesis, exchange analogously to the human L-arginine:glycine amidinotransferase, h-AGAT. F245N variant seems to lack the potential ligand-induced conformational changes. Higher activity of the F245N variant is enthalpy-driven -, 719473
Show all pathways known for 2.1.4.1Display the word mapDisplay the reaction diagram Show all sequences 2.1.4.1F245N/S247M site-directed mutagenesis, exchange analogously to the human L-arginine:glycine amidinotransferase, h-AGAT -, 719473
Show all pathways known for 2.1.4.1Display the word mapDisplay the reaction diagram Show all sequences 2.1.4.1medicine in vitro assay for enzyme activity in lymphocytes based on stable-isotope-labeled substrates L-(guanidino-15N2)arginine and U-(13C,15N)glycine 661505
Show all pathways known for 2.1.4.1Display the word mapDisplay the reaction diagram Show all sequences 2.1.4.1more the residue replacements do not change the kinetic mechanism of the three variant enzymes. The mutant protein variants have broad substrate specificity, e.g. the F245N variant additionally accepts creatine, with 7% relative activity -, 719473
Show all pathways known for 2.1.4.1Display the word mapDisplay the reaction diagram Show all sequences 2.1.4.1S247M site-directed mutagenesis, exchange analogously to the human L-arginine:glycine amidinotransferase, h-AGAT -, 719473
Results 1 - 5 of 5