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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204C292A about 3fold reduction in RNA binding affinity. Significant residual activity 710547
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204C79A about 3fold reduction in RNA binding affinity. No detectable in vitro methylation activity 710547
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204C79A site-directed mutagenesis, inactive mutant 718931
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204D217H site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme 735726
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204D226Y site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme 735726
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204D255Y site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme 735726
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204E119A mutant binds stronger to RNA than wild-type. No detectable in vitro methylation activity 710547
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204E119A site-directed mutagenesis, inactive mutant 718931
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204E185K site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme 735726
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.204E202Q site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme 735726
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