EC Number   |
Protein Variants |
Reference |
|---|
    1.8.1.14 | C43S |
the enzyme has ca. 0.03% activity relative to the wild type enzyme |
724355 |
| 1.8.1.14 | Y361F |
the mutant shows increased catalytic efficiency compared to the wild type enzyme |
724355 |
| 1.8.1.14 | Y361F/Y419F |
the mutant shows reduced catalytic efficiency compared to the wild type enzyme |
724355 |
| 1.8.1.14 | Y367/Y425F |
inactive mutant enzyme |
685242 |
| 1.8.1.14 | Y367F |
kcat for NADH is 3.9fold lower than wild-type value, kcat for NADPH is 5.6fold lower than wild-type value |
685242 |
| 1.8.1.14 | Y367F |
the mutant is 18% as active as wild type enzyme |
685242 |
| 1.8.1.14 | Y367F/Y425F |
inactive |
685242 |
| 1.8.1.14 | Y419F |
the mutant shows reduced catalytic efficiency compared to the wild type enzyme |
724355 |
| 1.8.1.14 | Y425F |
kcat for NADH is 30fold lower than wild-type value, kcat for NADPH is 93fold lower than wild-type value |
685242 |
| 1.8.1.14 | Y425F |
the mutant is 1% as active as wild type enzyme |
685242 |
