EC Number   |
Protein Variants |
Reference |
|---|
  1.4.1.8 | A124G |
lower activity toward aliphatic amino acid substrates, e.g. catalytic rate constant for oxidative deamination of L-valine is only 12% of the wild type, but higher activities toward L-phenylalanine, L-tyrosine, and L-methionine |
391700 |
| 1.4.1.8 | C251S |
kcat for deamination is 13% of the wild-type value |
675330 |
| 1.4.1.8 | C30S |
kcat for deamination is 13% of the wild-type value |
675330 |
| 1.4.1.8 | K79A |
lower affinity for L-valine and 2-oxoisovalerate and lower catalytic rate constants compared to the wild type enzyme |
391701 |
| 1.4.1.8 | K91A |
lower affinity for L-valine and 2-oxoisovalerate and lower catalytic rate constants compared to the wild type enzyme |
391701 |
| 1.4.1.8 | more |
active site lysine residue modified with pyridoxal 5-phosphate |
391701 |
| 1.4.1.8 | V305L |
kcat for deamination is 0.1% of the wild-type value |
675330 |
