EC Number   |
Protein Variants |
Reference |
|---|
   1.14.19.3 | A181T/A188G/Y189F/S205N/L206T/G207A |
compared to wild-type: reduced DELTA6 desaturase activity with palmitoyl-[acyl-carrier protein] as substrate, strong DELTA9 desaturase activity with stearoyl-[acyl-carrier protein] as substrate, exhibits DELTA9 desaturase activity with palmitoyl-[acyl-carrier protein] as substrate |
438436 |
| 1.14.19.3 | A181T/A200F |
increase in DELTA6 desaturase activity with palmitoyl-[acyl-carrier protein] as substrate, strong DELTA9 desaturase activity with stearoyl-[acyl-carrier protein] as substrate |
438436 |
| 1.14.19.3 | A181T/A200F/S205N/L206T/G207A |
reduced DELTA6 desaturase activity with palmitoyl-[acyl-carrier protein] as substrate, very low DELTA9 desaturase activity, no DELTA6 desaturase activity with stearoyl-[acyl-carrier protein] as substrate |
438436 |
| 1.14.19.3 | A188G/Y189F |
reduced DELTA6 desaturase activity with palmitoyl-[acyl-carrier protein] as substrate |
438436 |
| 1.14.19.3 | A361Q |
activity is significantly lower than that of wild-type enzyme |
745517 |
| 1.14.19.3 | D313I |
site-directed mutagenesis, mutant shows slightly reduced activity compared to the wild-type enzyme |
745520 |
| 1.14.19.3 | D367H |
site-directed mutagenesis, mutant shows similar activity compared to the wild-type enzyme |
745520 |
| 1.14.19.3 | DELTA238P/DELTA239L |
activity is significantly lower than that of wild-type enzyme |
745517 |
| 1.14.19.3 | DELTA238P/DELTA239L |
decreased or null DELTA6 desaturase activity |
745517 |
| 1.14.19.3 | E222S |
site-directed mutagenesis, the mutant's relative conversion rate of alpha-linolenoyl-CoA is reduced by almost 50% compared to the wild-type enzyme |
745514 |
