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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 1.14.14.74G312R natural genetic variant, almost complete loss of enzymatic activity. Loss of CO binding to the heme, molecular modelling predicts a spatial hindrance between heme and the bulky side chain of the R312 residue in G312R 744774
Display the reaction diagram Show all sequences 1.14.14.74more identification of 12 genetic variations from 93 Korean subjects 744774
Display the reaction diagram Show all sequences 1.14.14.74P351L natural genetic variant, activity similar to wild-type 744774
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