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Protein Variants:
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EC Number
Protein Variants
Commentary
Reference
1.14.11.55
A163C
residue is not involved in ligand binding
740868
1.14.11.55
A163C
the mutant shows reduced activity compared to the wild type enzyme
743087
1.14.11.55
A163C/S244C
residues are not involved in ligand binding
740868
1.14.11.55
A163C/S244C
the mutant shows increased activity compared to the wild type enzyme
743087
1.14.11.55
D148A
inactive
743087
1.14.11.55
D148A
loss of activity. Residue is involved in binding of Fe2+
740868
1.14.11.55
D148E
inactive
743087
1.14.11.55
D148E
loss of activity. Residue is involved in binding of Fe2+
740868
1.14.11.55
E140A
residue involved in dimerization, activity similar to wild-type
-
,
740729
1.14.11.55
F143A
inactive
743087
Results
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