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Results 1 - 5 of 5
EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.54D135I the mutant shows increased activity with RNA-N6-methyladenine and reduced activity with DNA-N1-methyladenine compared to the wild type enzyme 741601
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.54D135N the mutant shows increased activity with RNA-N6-methyladenine and reduced activity with DNA-N1-methyladenine compared to the wild type enzyme 741601
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.54E136L the mutant shows increased activity with RNA-N6-methyladenine and reduced activity with DNA-N1-methyladenine compared to the wild type enzyme 741601
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.54L177A mutation at the active site, mutant lost its demethylation activity on m1A of tRNA in vitro and in vivo 765483
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.54R122A mutant is defective in its DNA/RNA binding groove, mutant lost its demethylation activity on m1A of tRNA in vitro and in vivo 765483
Results 1 - 5 of 5