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EC Number
Protein Variants
Commentary
Reference
1.1.99.39
A208T
inactive
741050
1.1.99.39
A426T
inactive
741050
1.1.99.39
G131X
inactive
741050
1.1.99.39
I147S
D-2-hydroxyglutaric aciduria disease-related variant. The cofactor binding site is compromised by the single amino acid replacement. The variant forms aggregates that are unable to bind the FAD cofactor
762750
1.1.99.39
R212W
inactive
741050
1.1.99.39
R421H
inactive
741050
1.1.99.39
V444A
D-2-hydroxyglutaric aciduria disease-related variant. The cofactor binding site is compromised by the single amino acid replacement. The variant forms aggregates that are unable to bind the FAD cofactor
762750
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