EC Number   |
Protein Variants |
Reference |
|---|
  1.1.1.367 | F297Y |
mutation in the second co-ordination sphere of Zn2+, mutant exerts a minor effect on catalytic activity |
-, 726905 |
| 1.1.1.367 | H290L |
mutation in he coordination sphere of Zn2+. Mutant maintains a native-like dimeric conformation in solution, but does not generate a final product |
-, 726905 |
| 1.1.1.367 | H337L |
mutant displays diminished thermal stability |
-, 726905 |
| 1.1.1.367 | S94A/Y103A |
catalytic site of the short-chain dehydrogenase/reductase domain. Mutant maintains a native-like dimeric conformation in solution, but does not generate a final product. Addition of the reductase domain rescue the enzymatic activity |
-, 726905 |
| 1.1.1.367 | T364Y F297Y |
mutation in the second co-ordination sphere of Zn2+, mutant exerts a minor effect on catalytic activity |
-, 726905 |
