EC Number   |
Protein Variants |
Reference |
|---|
    1.1.1.26 | G165D |
mutation identified in patient with primary hyperoxaluria type 2, about 1.5% residual enzymic activity, enzyme is unstable upon purification |
655702 |
| 1.1.1.26 | more |
complementation of SSADH-deficient yeast with Arabidopsis thaliana GLYR1, the yeast then grows on 20 mM GABA as the sole nitrogen source and contains elevated levels of 4-hydroxybutyrate |
696125 |
| 1.1.1.26 | more |
construction of a E141N/Q313E mutant formate dehydrogenase which gains glyoxylate reductase activity improved through enhancement of the hydrogen transfer step in the catalytic process, while the replacement induces no marked activity toward other 2-koxoacid substrates, and diminishes the enzyme's activity as to formate oxidation, substrate specificity and kinetic switch of the mutant, overview |
684838 |
| 1.1.1.26 | more |
identification of point mutations and minor deletions resulting in primary hyperoxaluria type 2 |
655702 |
| 1.1.1.26 | more |
mutant lacking cytosolic hydroxypyruvate-metabolizing activity (HPR-1) |
286418 |
| 1.1.1.26 | R302C |
mutation identified in patient with primary hyperoxaluria type 2, about 5.6% residual enzymic activity, enzyme is unstable upon purification |
655702 |
| 1.1.1.26 | T335A |
nonphosphorylatable variant |
762165 |
| 1.1.1.26 | T335D |
phosphomimetic variant, exhibits reduced NADH-dependent hydroxypyruvate reductase activity while showing improved NADPH-dependent activity |
762165 |
