EC Number   |
Protein Variants |
Reference |
|---|
   1.1.1.206 | A160S |
higher Km for tropinone that wild type enzyme |
347972 |
| 1.1.1.206 | H112F |
higher Km for tropinone that wild type enzyme |
347972 |
| 1.1.1.206 | H112Y |
higher Km for tropinone that wild type enzyme |
347972 |
| 1.1.1.206 | more |
enzyme suppression in potato plants by RNA interference (RNAi) and enzyme overexpression. The overexpression and gene knockdown of StTRI alters tropinone reduction in vivo, but has no influence on calystegine accumulation,in contrast to genetic manipulation of isozyme St-TRII, EC 1.1.1.236, phenotypes, calystegine analysis overview. Higher availability of tropinone, when StTRI gene expression is reduced, and enhanced formation of pseudotropine, that may result in a higher calystegine accumulation, are not evident |
741221 |
| 1.1.1.206 | more |
overexpression of tropinone reductases TRI and TRII, EC 1.1.1.236, from Datura stramonium alters alkaloid composition in Atropa belladonna root cultures, overview |
656413 |
| 1.1.1.206 | more |
peptide exchanges with tropinone reductase II |
347969 |
| 1.1.1.206 | more |
various mutants: H112Y/A160S, A160S/V168E, V168E/H112Y, H112Y/A160S/V168E, I223L/F226L, H112Y/A160S/V168E/I223L/F226L, all mutants have different Km values for tropinone and NADPH |
347972 |
| 1.1.1.206 | V168E |
lower Km for tropinone that wild type enzyme |
347972 |
