EC Number   |
Protein Variants |
Reference |
|---|
    1.1.1.119 | D172K |
mutation in surface residue, mutant protein is slightly less halotolerant than wild-type |
686754 |
| 1.1.1.119 | D172K/D216K/D344K |
mutation in surface residue, mutant protein is slightly less halotolerant than wild-type |
686754 |
| 1.1.1.119 | D216K |
mutation in surface residue, mutant protein is slightly less halotolerant than wild-type |
686754 |
| 1.1.1.119 | D344K |
mutation in surface residue, mutant protein is slightly less halotolerant than wild-type |
686754 |
| 1.1.1.119 | D38C |
crystallization of a range of binary and ternary complexes of the wild-type and a D38C mutant protein |
-, 667073 |
| 1.1.1.119 | G206D |
less efficient with NADP+ than the wild type, 1.6fold increase in ratio kcat/Km for NAD+ |
699602 |
| 1.1.1.119 | G206D |
prefers NAD+ over NADP+ |
699602 |
| 1.1.1.119 | G206D |
the mutant is less efficient with NADP+ than the wild type enzyme, the relation kcat/KNAD+ is 1.6times higher than in the wild type, resulting in an enzyme that prefers NAD+ over NADP+ |
699602 |
| 1.1.1.119 | G206D/R207I |
active only with NAD+ |
699602 |
| 1.1.1.119 | G206D/R207I |
no activity with NADP+, highest reaction rate with cofactor NAD+ of all mutants tested |
699602 |
