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Results 1 - 10 of 12 > >>
EC Number
Amino acid exchange
Commentary
Reference
H166A
the mutant is partially active in forming Sec-tRNASec in vivo. In vitro, the mutant is partially active in forming Cys-tRNASec
H166F
mutant is inactive in vivo
H166Q
mutant is inactive in vivo
K173A
in vivo activity of the mutant is indistinguishable from that of the wild-type enzyme
K173M
in vivo activity of the mutant is indistinguishable from that of the wild-type enzyme
Q105A
mutant is inactive in vivo
R307A
the mutant is significantly less active in L-selenocysteinyl-tRNASec formation in vivo and Cys-tRNASec formation in vitro
R313A
mutant is inactive in vivo
R72A
the mutant enzyme is significantly less active in L-selenocysteinyl-tRNASec formation in vivo and Cys-tRNASec formation in vitro. The mutant enzyme is unable to form L-selenocysteinyl-tRNASec in vitro
R75A
mutant is inactive in vivo
Results 1 - 10 of 12 > >>