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Results 1 - 8 of 8
EC Number
Amino acid exchange
Commentary
Reference
K259A
the mutant shows 13.1% activity compared to the wild type enzyme
more
a synthetic siRNA duplex, si3-OST-3, corresponding to 3-OST-3 mRNA sequences is used to inhibit the expression of mRNAs encoding 3-OST-3 isoforms, downregulation of the expression of 3-OST-3 by RNA interference potently reduced CyPB binding and consequent activation of p44/42 mitogen-activated protein kinases, overview
more
construction of a truncated version of 3-OST-3A starting at amino acid position G148, thereby lacking the cytoplasmic, transmembrane and SPLAG domain
more
expression of 3-OST-3 leads to cell-to-cll fusion activity in CHO-K1 cells via gD receptors modified with 3-OS HS generated by 3-OST-3, overview
T256A
the mutant shows 101.5% activity compared to the wild type enzyme
T256E
the mutant shows 13.1% activity compared to the wild type enzyme
T256V
the mutant shows 59.4% activity compared to the wild type enzyme
W283A
the mutant shows 7.6% activity compared to the wild type enzyme
Results 1 - 8 of 8