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Results 1 - 10 of 17 > >>
EC Number
Amino acid exchange
Commentary
Reference
C3S/C5S
PSD-95aC3S/C5S mutant
D103N
active
D74A
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
E101D
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
E72Q
no guanylate or adenylate kinase activity
E72Q/D103D
no active
more
construction of mutant PSD-95 SH3-GK which contains a deleterious point mutation in the C-terminal SH3 domain
more
RNAi knockdown of the cytosolic enzyme, a v2 mutant is temperature-sensitive and develops chlorotic leaves at restrictive temperatures, the v2 mutation causes inhibition of chloroplast differentiation; in particular, it disrupts the chloroplast translation machinery during early leaf development
N103D
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
P564S/S631D
PSD-95 construct
Results 1 - 10 of 17 > >>