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Results 1 - 7 of 7
EC Number
Amino acid exchange
Commentary
Reference
K213A
subunit PabB, numbering used is based on the EntC protein from Escherichia coli, reduced activity
K213A/Q147K
subunit PabB, numbering used is based on the EntC protein from Escherichia coli, strongly reduced activity
K274A
265fold reduction of kcat-value
K274A/L277R/D299E/N303H/I306L/F334Y/C391G
mutant displaying anthranilate synthase activity, the kcat/Kchoris value for anthranilate formation is 25% of the wild-type aminodeoxychorismate synthase value for 4-amino-4-deoxychorismate production
K274R
640fold reduction of kcat-value
N213V/L214P/K274A/L277R/D299E/N303H/F334Y/P363N/I367L/C391G/G425A
mutant displaying anthranilate synthase activity, is able to produce both 2-amino-2-deoxyisochorismate and anthranilate
N213V/L214P/R259S/K274A/L277R/N303H/F334Y/S366T/C391G/G254A
mutant displaying anthranilate synthase activity, is able to produce both 2-amino-2-deoxyisochorismate and anthranilate
Results 1 - 7 of 7