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EC Number
Protein Variants
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1.2.1.100
E149Q
mutant shows a showed a different pH optimum depending on the cosubstrate. With NAD+, the mutant shows very low activity with an optimum pH at 8.5 in the universal buffer. In contrast, the optimum pH is 5.5 with NADH
745236
1.2.1.100
H137L
almost complete loss of activity
745236
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