EC Number   |
Protein Variants |
Reference  |
|---|
    1.13.11.3 | Y447H |
greatly reduced rate of protocatechuate oxygenation |
439508 |
| 1.13.11.3 | R133H |
gain of function mutation confers catechol 1,2-dioxygenase activity |
-, 439509 |
| 1.13.11.3 | R142K |
like wild-type no acticity of mutated protocatechuate 3,4-dioxygenase I with 4-sulfocatechol |
439513 |
| 1.13.11.3 | R142K/W153V |
protocatechuate 3,4-dioxygenase I gain of function mutation, mutant enzyme oxidizes 4-sulfocatechol |
439513 |
| 1.13.11.3 | R153V |
protocatechuate 3,4-dioxygenase I gain of function mutation, mutant enzyme oxidizes 4-sulfocatechol |
439513 |
| 1.13.11.3 | DELTA319-322 |
turnover-number is 4.14fold lower than that of the wild-type enzyme, the Km-value for 3,4-dihydroxybenzoate is 2.1fold lower than that of the wild-type enzyme |
657551 |
| 1.13.11.3 | R133H |
turnover-number is fold 500lower than that of the wild-type enzyme, the Km-value for 3,4-dihydroxybenzoate is 1.8fold higher than that of the wild-type enzyme |
657551 |
| 1.13.11.3 | R457S |
turnover-number is 1333fold lower than that of the wild-type enzyme, the Km-value for 3,4-dihydroxybenzoate is 2.2fold lower than that of the wild-type enzyme |
657551 |
| 1.13.11.3 | Y408C |
turnover-number is 523fold lower than that of the wild-type enzyme |
657551 |
| 1.13.11.3 | Y408E |
turnover-number is 6800fold lower than that of the wild-type enzyme |
657551 |
