EC Number   |
Protein Variants |
Reference  |
|---|
   1.11.1.5 | W191G |
provides a specific site near heme from which substrates might be oxidized |
394628 |
| 1.11.1.5 | R48K |
hexacoordinate, high-spin, unreactive against H2O2 |
394629, 394630 |
| 1.11.1.5 | R48L |
reacts with H2O2 at a lower rate |
394629, 394630 |
| 1.11.1.5 | D235N |
predominantly hexacoordinate between pH 4 and pH8 |
394630 |
| 1.11.1.5 | H52L |
reacts with H2O2 at a lower rate |
394630 |
| 1.11.1.5 | W191F |
reacts with H2O2 at a slightly higher rate |
394630 |
| 1.11.1.5 | more |
distal pocket mutants, proximal pocket mutants, channel mutants, surface mutations |
394631 |
| 1.11.1.5 | more |
mutant with deletion of the translation start codon and 800 bp of the enzyme gene. Almost as active as the wild-type enzyme |
657830 |
| 1.11.1.5 | H52L |
with slower cyanide dissociation rate constant for the heme group with respect to the wild-type enzyme |
657943 |
| 1.11.1.5 | H52L |
exhibits multiple forms in solution, with a reversible temperature-dependent interconversion, indicating the presence of a dynamic equilibrium between enzyme forms, which favors an apparent single form at low temperature and low pH, and a different form at high temperature and high pH |
657944 |
