EC Number |
Protein Variants |
Reference |
---|
5.1.1.5 | T224I |
site-directed mutagenesis, the mutant shows significantly decreased activity compared to the wild-type enzyme |
727795 |
5.1.1.5 | T224I/W355Y |
site-directed mutagenesis, the double mutant shows significantly decreased activity compared to the wild-type enzyme |
727795 |
5.1.1.5 | T391Y |
site-directed mutagenesis, the mutant shows 47% reduced activity with L-lysine compared to the wild-type enzyme |
-, 728587 |
5.1.1.5 | T391Y/S394Y |
site-directed mutagenesis,the mutant exhibits significantly reduced specific activity towards L-Lys (6% residual activity) and toward L-Arg (0.9% residual activity) |
728587 |
5.1.1.5 | W355Y |
site-directed mutagenesis, the mutant shows significantly decreased activity compared to the wild-type enzyme |
727795 |