EC Number   |
Protein Variants |
Reference |
|---|
   3.1.3.75 | D32N |
site-directed mutagenesis, inactive mutant enzyme fragment |
664211 |
| 3.1.3.75 | D33E |
protein expression, but no enzyme activity |
679380 |
| 3.1.3.75 | D43N |
site-directed mutagenesis, the mutant enzyme fragment shows reduced activity compared to the wild-type enzyme fragment |
664211 |
| 3.1.3.75 | D43N/D123N |
site-directed mutagenesis, inactive mutant enzyme fragment |
664211 |
| 3.1.3.75 | E42A |
site-directed mutagenesis |
714357 |
| 3.1.3.75 | E43A |
site-directed mutagenesis |
714357 |
| 3.1.3.75 | G261A |
reduced activity as compared to wild-type |
679380 |
| 3.1.3.75 | K242Q |
is inactive |
679380 |
| 3.1.3.75 | K242R |
functional enzyme |
679380 |
| 3.1.3.75 | more |
generation of phospho1-R74X-null mutant, i.e. Phospho1-/-, mice by N-ethyl-N-nitrosourea mutagenesis |
-, 714633, 715704 |
